Paul Serban Popa, Monica Rarinca-Bîrsan, Marius Moroianu, Gabriel G. Condurache, Radu Dolișcinschi, Ionuța Grigore, Kamel Earar
Sepsis is a generalized infectious condition caused by the spread of a non- pathogenic germ (i.e. a germ that can cause disease) throughout the body, through the blood, also known as the sepsis; is a life-threatening complication that can occur when bacteria, from another infection, enter the bloodstream and spread throughout the body. Normally, the bloodstream does not contain microbes, but when the bacteria enters it, is called bacteremia. If bacteria multiply, the body reacts by releasing chemicals into the bloodstream. These substances cause an inflammatory response that can cause damage to body organs. Septicemia requires urgent treatment in the hospital, as it can quickly lead to the destruction of healthy tissues, organ failure and death. Without treatment, this condition can be fatal.
Treating septicemia with antibiotics can prevent septic shock. The infections that most commonly lead to sepsis are pneumonia, followed by urinary tract infections, gastrointestinal infections, and skin or soft tissue infections. Sepsis is a severe complication of infections. Other complications depend on the degree of damage to the organs. Complications also depend on the general health of the individual and how quickly the treatment against the infection is obtained. The vast majority of people who rehabilitate after severe sepsis have a long-term evolution without problems.
However, some people may suffer permanent organ damage. This is much more likely for those with long-term conditions such as kidney failure. In some cases, the immune system may also be affected; this may increase the likelihood of future infections. Rehabilitating this diagnosis is quite difficult.